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equipoise results

Equipoise results – complex antianemic preparation containing divalent iron in the simple salt form of iron sulfate,  , folic and ascorbic acid for the treatment of iron deficiency states. Iron is an important part of the human body. It is part of hemoglobin, myoglobin and various other enzymes. Ascorbic acid enhances iron absorption in the intestine. Vitamin B 12 and folic acid are involved in the formation and maturation of erythrocytes.
The active ingredients of the drug are  special envelope that promotes absorption, mainly in the upper part of the small intestine. The lack of a local irritant to the stomach contributes to a good tolerability of the drug from the gastrointestinal tract.

Indications

Combined iron-folic acid-in the 12 -scarce anemia due to chronic blood loss (gastric, intestinal bleeding, bleeding from the bladder, hemorrhoids, Meno-metrorrhagia), as well as chronic alcoholism, infections, taking antiseizure drugs and oral contraceptives; anemia during pregnancy and lactation.
Prevention of iron and folic acid deficiency in the second and third trimesters of pregnancy, the postpartum period, during breast-feeding.

Contraindications

Anemia not caused by iron deficiency , hypersensitivity, liver failure.
Excess iron in the body (eg, hemosiderosis, hemochromatosis).
The disorder of iron recovery mechanisms (eg lead anemia , sideroahrestical anemia).

Dosing and Administration

Inside 1-2 capsules after meals. Anemia: a mild form of 1 capsule 3 times daily for 3-4 weeks; at medium-severe – 1 capsule 3 times daily for 8-12 weeks; in severe – 2 capsules 3 times a day for 16 weeks or more. During pregnancy – for preventing lack of folic acid and iron – 1 capsule 3 times a day for 2 or 3 trimesters, postpartum during lactation.

Side effect

Nausea, allergic reactions: eczema equipoise results phenomenon, hives, anaphylactic shock, anaphylactoid reactions.

Overdose

It is characterized by the appearance of epigastric pain, nausea, vomiting, stool disorders, drowsiness, pallor, the development of shock up to coma. Recommended treatment measures include gastric lavage, the appointment desferroksamina and organization of adequate maintenance therapy.

Interaction with other drugs

Organic acids, calcium salts, phosphates, phytin, cholestyramine and antacids containing aluminum, magnesium, calcium, iron absorption due to disrupt formation of insoluble complexes. Preparations containing pancreatic enzymes, can reduce the absorption of iron.
With simultaneous use of phenobarbital, carbamazepine, valproate, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, pyrimethamine and triamterona reduced folate digestibility.
Iron salts violate absorption in the gastrointestinal tract of antibiotics tetracycline group.
Solid food, bread, raw cereals, dairy equipoise results products, eggs, reduce the absorption of iron, while the appointment with the antibiotics tetracycline group and also with penicillinamine form complex compounds that reduce iron absorption and reduce the antimicrobial activity of antibiotics.

Special instructions :

The dark color of the chair due to breeding not grown deep iron and has no clinical significance.

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eq steroid

A means for the treatment and prevention of iron deficiency
drug contains as active ingredients ferrous fumarate and folic acid. Iron fumarate – an iron salt, a trace element necessary for the synthesis of hemoglobin. When using iron in the form of salts, there is a rapid replenishment of its deficiency in the body, which leads to a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, pain and dryness of the skin) and laboratory symptoms of anemia. Folic acid is essential for normal maturation and education megaloblasts normoblasts. It stimulates erythropoiesis, is involved in the synthesis clenox
of amino acids, nucleic acids, purine and pyrimidine metabolism in choline. During pregnancy protects the body from the effects of teratogens. Eq steroid contributes to the maintenance and restoration of normal levels of iron in the blood and prevents complications such as anemia, miscarriage, early labor and violation of children’s mental development, which can be observed with a deficiency of iron and folic acid in the body. The amount of assimilable iron is between 5 and 35%.
The serum transferrin bound iron and is involved in the formation of hemoglobin, myoglobin, cytochrome oxidase, catalase and peroxidase or stored in body tissues in the form of ferritin.

Pharmacokinetics
iron allocation occurs in the feces, urine and sweat. Folic acid is absorbed primarily in the upper gastrointestinal tract (duodenum) and 64% bound proteins. Folic acid is metabolized in the liver and excreted primarily through the kidneys and partially with faeces.

Indications

Treatment and prevention of iron deficiency caused by pregnancy, impaired iron absorption from the gastrointestinal tract, prolonged bleeding, malnutrition and unbalanced.

Contraindications

Hypersensitivity to the drug. Diseases accompanied by accumulation of iron in the body (aplastic and haemolytic anemia, thalassemia, hemosiderosis, hemochromatosis). Violation of the absorption of iron (sideroahrestical anemia, lead anemia, pernicious anemia (vitamin B12 deficiency). The anemia that is not caused by iron deficiency or folic acid.

Dosing and Administration

Ferretab COMP taken orally, 1 capsule per day on an empty stomach, abundant with some liquid. When expressed iron deficiency or folic acid dose should be increased to two or three capsules a day.Maintenance eq steroid treatment should be continued for at least 4 weeks after the normal hemoglobin level for the normalization of serum ferritin, which reflects iron stores in the body.

Side effect

Ferretab COMP is well tolerated by patients.
In some cases there may be a temporary adverse effect on the gastrointestinal tract (feeling of fullness and discomfort in the stomach, nausea, vomiting), and allergic reactions, constipation.

Overdose

Symptoms – possibly increasing incidence described side effects. If you suspect an overdose, it is necessary to conduct a study of serum iron and serum ferritin levels. In the event of a significant excess of normal values of serum ferritin should be the appointment of iron chelator (Desferal) in accordance with the recommended dose of the manufacturer.

Interaction with other drugs

When concomitantly with antacids  eq steroid iron absorption worsens.
Simultaneous treatment with ascorbic acid improves iron absorption.
Avoid joint use with antibiotics of the tetracycline group in connection with the violation of iron absorption. Kolestiramin, phenytoin, phenobarbital, carbamazepine, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, triamterene, solid food, bread, raw cereals, dairy products, eggs, tea reduces iron absorption.

special instructions

Before therapy of iron supplementation is necessary to conduct a study of serum iron, serum ferritin (ie documented iron deficiency).
Therapy Ferretab COMP should be done to normalize the blood picture (8-12 weeks).
Before the drug can be dark fecal staining, benzidine test – false-positive.

Use during pregnancy and lactation

Perhaps the  during pregnancy and during breast-feeding when indicated

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equipoise dosage

Combination drug whose action is due to the properties of its constituent components.
Iron is an essential component of hemoglobin, which carries oxygen transport to the tissues. Equipoise dosageand pantothenic acid, zinc – needed for the formation of red blood cells and the synthesis of amino acids, contribute to the normalization of erythropoiesis.  Copper increase the efficiency of iron absorption. Manganese regulates carbohydrate metabolism. Restores iron deficiency, minerals, B vitamins lead to a normalization of hemoglobin biosynthesis and activation of the whole complex redox processes, eliminating the related symptoms of anemia – general weakness and lethargy, increasing physical and mental activity.

Indications.
Prevention of iron and vitamin B- 12 -scarce states due to:

  • unbalanced and malnutrition;
  • malabsorption in the gastrointestinal tract;
  • increased demand (during pregnancy and lactation in the period of active growth in children and adolescents).

Contraindications.
Hypersensitivity to the drug.
Dosage and administration. Ingest after meals. Children:

  • 1-3 years – ½ teaspoon per day
  • 4-6 years – ½ tsp 2 times a day
  • 7-12 years – 1 teaspoon 1-2 times a day

Teenagers: 1 teaspoon 3 times a day Adults: 1 teaspoon 2 times a day. During menstruation, pregnancy and equipoise dosage breastfeeding is recommended 1 teaspoon 3 times a day.

 

Side effects.
Allergic reaction.

Interactions with other drugs.
It is not recommended concomitant use of other multivitamin complexes.

Special instructions.
Perhaps staining of urine bright yellow color (completely harmless and is caused by the presence of riboflavin in the composition of the drug).

Product Form
In 50 or 200 ml bottles of polyethylene equipoise dosage terephthalate brown screw-cap polypropylene opening by pressing. 1 bottle with instruction on the medical application is placed in a cardboard box.

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equipoise cycle

Ferlatum – iron formulation replenishes the lack of iron in the body. The main function of iron is to carry oxygen to the tissues. The iron part of hemoglobin, myoglobin, cytochrome iron-containing enzymes, and transfers electrons acts as a catalyst of oxidation reactions, hydroxylation and other metabolic processes.Ferlatum contains iron suktsinilat protein, which is a complex compound in which atoms of ferric iron (Fe3 +) are surrounded by a semi-synthetic protein carrier, preventing damage to the gastric mucosa. The protein carrier is dissolved again in the duodenum, liberating iron in place of its better absorption. From the intestine into the blood equipoise cycle ferric goes through active absorption, which explains the impossibility of overdose and poisoning.

 

Indications for use:

 

  • Treatment of latent and symptomatic iron deficiency (iron deficiency anemia);
  • Preventive treatment of iron deficiency during pregnancy, lactation, active growth;After prolonged bleeding, against defective and unbalanced diet.

    Contraindications:

  • Hypersensitivity to the drug;
  • Iron overload (hemochromatosis);
  • Violation of iron utilization (lead anemia, sideroahrestical anemia);
  • Nezhelezodefitsitnye anemia (hemolytic anemia, megaloblastic anemia caused by lack of vitamin B12);
  • Chronic pancreatitis;
  • Cirrhosis of the liver.Pregnancy and lactation
    Use of the drug Ferlatum can be recommended for the prevention and treatment of iron deficiency that develops during pregnancy and lactation. 

    Dosage and administration:

    Ferlatum taken orally before or after a meal.
    Adults: 1-2 bottle daily amount equivalent to 40-80 mg of Fe3 + or doctor in accordance with the recommendations in 2 hours.
    Children: 1.5 ml / kg / day (in an amount equivalent to 4 mg / kg / day, Fe3 +) in 2 hours or according to a physician’s recommendations.

    Pregnant women:
    For the prevention of iron deficiency equipoise cycle anemia – 1 bottle per day. For the treatment of latent or symptomatic iron deficiency – 1-2 bottles a day in 2 divided doses. After reaching normal levels of hemoglobin and serum iron treatment is continued for at least 8-12 weeks, assigning a maintenance dose.

    Side effects:
    In rare cases, may cause gastro-intestinal disorders (including diarrhea, constipation, nausea and epigastric pain), usually using higher doses Ferlatuma that disappear with dose reduction or withdrawal of the drug.

     

    Overdose:

    So far it has not been described signs of intoxication and excess revenues Ferlatum the drug into the body.However, the first 6-8 hours after the application of excessive doses of iron preparations may cause epigastric pain, nausea, vomiting (sometimes with blood), diarrhea, in some cases accompanied by lethargy, pale skin.Perhaps the development of shock up to coma.Immediate therapeutic measures to the provision of skilled care include gastric lavage.

     

    Interaction with other drugs:

    There was no interaction Ferlatuma with other drugs.However, iron tetracycline derivatives contribute to disruption of absorption in the gastrointestinal tract and thereby avoid the simultaneous application of them.iron absorption can be increased with concomitant administration of 200 mg of ascorbic acid and reduced by the application of antacids.Chloramphenicol is a delayed response to iron therapy.Noting the absence of pharmacological interaction with concomitant treatment of H2-receptor antagonists.

     

    Special instructions:

    Continuous application period equipoise cycle should not exceed 6 months, except in cases of chronic blood loss (menorrhagia, haemorrhoids, etc.) And pregnancy.It does not affect the classes of potentially hazardous activities that require high concentration and speed of psychomotor reactions (including driving motor vehicles).

     

    Product form:

    Oral solution 800 mg 15 ml in plastic vials, sealed with plastic covers to control the first opening. 10 or 20 vials with the instruction in the carton box.

 

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define equipoise

Ferezol has a cauterizing effect, coagulates the proteins of the skin.
Normal, threadlike, and plantar warts, papillomas, genital skin warts, corns, keratomas.

Contraindications
Individual hypersensitivity to the drug. Pigmented nevi (moles), rash, located on the red border of the lips and mucous membranes. Do not apply the drug on the surface of the skin define equipoise
Children under 7 years old.

Use during pregnancy and lactation
Use of the drug is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus or child. During the period of lactation is not recommended to remove the formations on the breast and hands.

Dosing and Administration
Ferezol intended for external use only.
The product is applied exactly on the treated section of small thin wooden stick, avoiding contact with it on adjacent healthy areas of the skin and mucous membranes.
In the small papillomavirus (up to 2 mm) filamentous warts Ferezol applied once .
larger papillomas and warts are small (2-3 mm in size) lubricate the drug 3-4 times, taking breaks for drying the applied liquid.
Before removing warts Ferezolom with a dense surface on chapped hands, plantar warts, keratitis, dry calluses must be removed from their the surface of the horny layers. For this is applied for several hours keratolytic ointment (for example, 10% or salicylic al.), Covering the greased portion compress paper or plastic film, and then using a gauze bandage. Perhaps sealing the plaster. Then a bandage or adhesive plaster is removed, the skin steamed in hot water with soap and soda for 10-15 minutes and remove horny layers (cut with nail scissors or forceps). On the dried skin Ferezol applied several times, making a 3-4 minute breaks for drying of the drug.
The warts on the hands and soles of the processed drug Ferezol 7-10 times with an interval of 3-4 minutes.
Keratomas and dry corn enough to process 3-4 times with an interval 3-4 min.
If necessary, multiple application of the drug to avoid burn the surrounding skin it is advisable to coat it with zinc paste. The define equipoise paste is removed with dry gauze after drying of the last portion of Ferezola.
Genital warts is not recommended to remove yourself Ferezolom their treatment is carried out in the treatment room clinic dermatologist or urologist. Preparation Ferezol applied to each element separately 1-2 times at intervals of 3-4 min.
The re-processing is performed, if necessary after 6-8 days after falling away crust. Allowed to conduct 4-5 procedures.

Side effects:
Swelling and redness of the skin when applied to the eye area, going on their own. Allergic reactions.

Interaction with other medicinal products
Components preparation easily dissolve in the ointment base in connection with which to lubricate any ointments Ferezolom treated area of skin is not recommended.

Cautions
Do not allow contact with the drug on the mucous membranes, especially in the mucous membrane of eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
It is unacceptable bandaging plots treated with the drug, gluing of plaster, smearing any ointments and removing crusts; can not be re-applied preparation before the terms specified above. Clothing made of synthetic fabrics should not touch the skin area treated with the drug.
Do not apply Ferezol on education, located in the skin folds (inguinal folds, the anal region, interdigital spaces, etc.) And strongly sweating areas to avoid burns unaffected skin contacting surface or as a result of the spreading of the preparation on wet skin.
Crafted Ferezolom area of skin should be allowed to air dry, it can not be lubricated by any ointments, wash with water for the define equipoise first day after treatment.
in case of accidental contact with the drug on healthy skin must be immediately and carefully, not rubbing, remove it with the skin, and then treat the affected area 10-40% ethyl alcohol or alcohol-containing liquids (vodka, lotion, cologne) and wash thoroughly with warm soapy water.
recommended burns and healing remedy for scalds. When used properly, the drug does not leave scars.
Extreme care and caution is required in the treatment of drug children.

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