Equipoise results – complex antianemic preparation containing divalent iron in the simple salt form of iron sulfate, , folic and ascorbic acid for the treatment of iron deficiency states. Iron is an important part of the human body. It is part of hemoglobin, myoglobin and various other enzymes. Ascorbic acid enhances iron absorption in the intestine. Vitamin B 12 and folic acid are involved in the formation and maturation of erythrocytes.
The active ingredients of the drug are special envelope that promotes absorption, mainly in the upper part of the small intestine. The lack of a local irritant to the stomach contributes to a good tolerability of the drug from the gastrointestinal tract.
Combined iron-folic acid-in the 12 -scarce anemia due to chronic blood loss (gastric, intestinal bleeding, bleeding from the bladder, hemorrhoids, Meno-metrorrhagia), as well as chronic alcoholism, infections, taking antiseizure drugs and oral contraceptives; anemia during pregnancy and lactation.
Prevention of iron and folic acid deficiency in the second and third trimesters of pregnancy, the postpartum period, during breast-feeding.
Anemia not caused by iron deficiency , hypersensitivity, liver failure.
Excess iron in the body (eg, hemosiderosis, hemochromatosis).
The disorder of iron recovery mechanisms (eg lead anemia , sideroahrestical anemia).
Dosing and Administration
Inside 1-2 capsules after meals. Anemia: a mild form of 1 capsule 3 times daily for 3-4 weeks; at medium-severe – 1 capsule 3 times daily for 8-12 weeks; in severe – 2 capsules 3 times a day for 16 weeks or more. During pregnancy – for preventing lack of folic acid and iron – 1 capsule 3 times a day for 2 or 3 trimesters, postpartum during lactation.
Nausea, allergic reactions: eczema equipoise results phenomenon, hives, anaphylactic shock, anaphylactoid reactions.
It is characterized by the appearance of epigastric pain, nausea, vomiting, stool disorders, drowsiness, pallor, the development of shock up to coma. Recommended treatment measures include gastric lavage, the appointment desferroksamina and organization of adequate maintenance therapy.
Interaction with other drugs
Organic acids, calcium salts, phosphates, phytin, cholestyramine and antacids containing aluminum, magnesium, calcium, iron absorption due to disrupt formation of insoluble complexes. Preparations containing pancreatic enzymes, can reduce the absorption of iron.
With simultaneous use of phenobarbital, carbamazepine, valproate, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, pyrimethamine and triamterona reduced folate digestibility.
Iron salts violate absorption in the gastrointestinal tract of antibiotics tetracycline group.
Solid food, bread, raw cereals, dairy equipoise results products, eggs, reduce the absorption of iron, while the appointment with the antibiotics tetracycline group and also with penicillinamine form complex compounds that reduce iron absorption and reduce the antimicrobial activity of antibiotics.
Special instructions :
The dark color of the chair due to breeding not grown deep iron and has no clinical significance.