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equipoise results

Equipoise results – complex antianemic preparation containing divalent iron in the simple salt form of iron sulfate,  , folic and ascorbic acid for the treatment of iron deficiency states. Iron is an important part of the human body. It is part of hemoglobin, myoglobin and various other enzymes. Ascorbic acid enhances iron absorption in the intestine. Vitamin B 12 and folic acid are involved in the formation and maturation of erythrocytes.
The active ingredients of the drug are  special envelope that promotes absorption, mainly in the upper part of the small intestine. The lack of a local irritant to the stomach contributes to a good tolerability of the drug from the gastrointestinal tract.

Indications

Combined iron-folic acid-in the 12 -scarce anemia due to chronic blood loss (gastric, intestinal bleeding, bleeding from the bladder, hemorrhoids, Meno-metrorrhagia), as well as chronic alcoholism, infections, taking antiseizure drugs and oral contraceptives; anemia during pregnancy and lactation.
Prevention of iron and folic acid deficiency in the second and third trimesters of pregnancy, the postpartum period, during breast-feeding.

Contraindications

Anemia not caused by iron deficiency , hypersensitivity, liver failure.
Excess iron in the body (eg, hemosiderosis, hemochromatosis).
The disorder of iron recovery mechanisms (eg lead anemia , sideroahrestical anemia).

Dosing and Administration

Inside 1-2 capsules after meals. Anemia: a mild form of 1 capsule 3 times daily for 3-4 weeks; at medium-severe – 1 capsule 3 times daily for 8-12 weeks; in severe – 2 capsules 3 times a day for 16 weeks or more. During pregnancy – for preventing lack of folic acid and iron – 1 capsule 3 times a day for 2 or 3 trimesters, postpartum during lactation.

Side effect

Nausea, allergic reactions: eczema equipoise results phenomenon, hives, anaphylactic shock, anaphylactoid reactions.

Overdose

It is characterized by the appearance of epigastric pain, nausea, vomiting, stool disorders, drowsiness, pallor, the development of shock up to coma. Recommended treatment measures include gastric lavage, the appointment desferroksamina and organization of adequate maintenance therapy.

Interaction with other drugs

Organic acids, calcium salts, phosphates, phytin, cholestyramine and antacids containing aluminum, magnesium, calcium, iron absorption due to disrupt formation of insoluble complexes. Preparations containing pancreatic enzymes, can reduce the absorption of iron.
With simultaneous use of phenobarbital, carbamazepine, valproate, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, pyrimethamine and triamterona reduced folate digestibility.
Iron salts violate absorption in the gastrointestinal tract of antibiotics tetracycline group.
Solid food, bread, raw cereals, dairy equipoise results products, eggs, reduce the absorption of iron, while the appointment with the antibiotics tetracycline group and also with penicillinamine form complex compounds that reduce iron absorption and reduce the antimicrobial activity of antibiotics.

Special instructions :

The dark color of the chair due to breeding not grown deep iron and has no clinical significance.

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eq steroid

A means for the treatment and prevention of iron deficiency
drug contains as active ingredients ferrous fumarate and folic acid. Iron fumarate – an iron salt, a trace element necessary for the synthesis of hemoglobin. When using iron in the form of salts, there is a rapid replenishment of its deficiency in the body, which leads to a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, pain and dryness of the skin) and laboratory symptoms of anemia. Folic acid is essential for normal maturation and education megaloblasts normoblasts. It stimulates erythropoiesis, is involved in the synthesis of amino acids, nucleic acids, purine and pyrimidine metabolism in choline. During pregnancy protects the body from the effects of teratogens. Eq steroid contributes to the maintenance and restoration of normal levels of iron in the blood and prevents complications such as anemia, miscarriage, early labor and violation of children’s mental development, which can be observed with a deficiency of iron and folic acid in the body. The amount of assimilable iron is between 5 and 35%.
The serum transferrin bound iron and is involved in the formation of hemoglobin, myoglobin, cytochrome oxidase, catalase and peroxidase or stored in body tissues in the form of ferritin.

Pharmacokinetics
iron allocation occurs in the feces, urine and sweat. Folic acid is absorbed primarily in the upper gastrointestinal tract (duodenum) and 64% bound proteins. Folic acid is metabolized in the liver and excreted primarily through the kidneys and partially with faeces.

Indications

Treatment and prevention of iron deficiency caused by pregnancy, impaired iron absorption from the gastrointestinal tract, prolonged bleeding, malnutrition and unbalanced.

Contraindications

Hypersensitivity to the drug. Diseases accompanied by accumulation of iron in the body (aplastic and haemolytic anemia, thalassemia, hemosiderosis, hemochromatosis). Violation of the absorption of iron (sideroahrestical anemia, lead anemia, pernicious anemia (vitamin B12 deficiency). The anemia that is not caused by iron deficiency or folic acid.

Dosing and Administration

Ferretab COMP taken orally, 1 capsule per day on an empty stomach, abundant with some liquid. When expressed iron deficiency or folic acid dose should be increased to two or three capsules a day.Maintenance eq steroid treatment should be continued for at least 4 weeks after the normal hemoglobin level for the normalization of serum ferritin, which reflects iron stores in the body.

Side effect

Ferretab COMP is well tolerated by patients.
In some cases there may be a temporary adverse effect on the gastrointestinal tract (feeling of fullness and discomfort in the stomach, nausea, vomiting), and allergic reactions, constipation.

Overdose

Symptoms – possibly increasing incidence described side effects. If you suspect an overdose, it is necessary to conduct a study of serum iron and serum ferritin levels. In the event of a significant excess of normal values of serum ferritin should be the appointment of iron chelator (Desferal) in accordance with the recommended dose of the manufacturer.

Interaction with other drugs

When concomitantly with antacids  eq steroid iron absorption worsens.
Simultaneous treatment with ascorbic acid improves iron absorption.
Avoid joint use with antibiotics of the tetracycline group in connection with the violation of iron absorption. Kolestiramin, phenytoin, phenobarbital, carbamazepine, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, triamterene, solid food, bread, raw cereals, dairy products, eggs, tea reduces iron absorption.

special instructions

Before therapy of iron supplementation is necessary to conduct a study of serum iron, serum ferritin (ie documented iron deficiency).
Therapy Ferretab COMP should be done to normalize the blood picture (8-12 weeks).
Before the drug can be dark fecal staining, benzidine test – false-positive.

Use during pregnancy and lactation

Perhaps the  during pregnancy and during breast-feeding when indicated

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equipoise dosage

Combination drug whose action is due to the properties of its constituent components.
Iron is an essential component of hemoglobin, which carries oxygen transport to the tissues. Equipoise dosageand pantothenic acid, zinc – needed for the formation of red blood cells and the synthesis of amino acids, contribute to the normalization of erythropoiesis.  Copper increase the efficiency of iron absorption. Manganese regulates carbohydrate metabolism. Restores iron deficiency, minerals, B vitamins lead to a normalization of hemoglobin biosynthesis and activation of the whole complex redox processes, eliminating the related symptoms of anemia – general weakness and lethargy, increasing physical and mental activity.

Indications.
Prevention of iron and vitamin B- 12 -scarce states due to:

  • unbalanced and malnutrition;
  • malabsorption in the gastrointestinal tract;
  • increased demand (during pregnancy and lactation in the period of active growth in children and adolescents).

Contraindications.
Hypersensitivity to the drug.
Dosage and administration. Ingest after meals. Children:

  • 1-3 years – ½ teaspoon per day
  • 4-6 years – ½ tsp 2 times a day
  • 7-12 years – 1 teaspoon 1-2 times a day

Teenagers: 1 teaspoon 3 times a day Adults: 1 teaspoon 2 times a day. During menstruation, pregnancy and equipoise dosage breastfeeding is recommended 1 teaspoon 3 times a day.

 

Side effects.
Allergic reaction.

Interactions with other drugs.
It is not recommended concomitant use of other multivitamin complexes.

Special instructions.
Perhaps staining of urine bright yellow color (completely harmless and is caused by the presence of riboflavin in the composition of the drug).

Product Form
In 50 or 200 ml bottles of polyethylene equipoise dosage terephthalate brown screw-cap polypropylene opening by pressing. 1 bottle with instruction on the medical application is placed in a cardboard box.