Equipoise definition – nootropic drug has a pronounced antiamnestic action has a direct activating effect on the integrative activity of the brain contributes to memory consolidation, improves concentration and mental performance, facilitates the learning process, increases the speed of information transfer between the hemispheres of the brain, increases resistance to brain tissue hypoxia and toxic effects, possesses anticonvulsant action and anxiolytic activity, regulates the processes of the central nervous system activation and inhibition, improves mood.

Fenotropil has a positive effect on the metabolism and blood circulation of the brain, stimulates the redox processes, improves the body’s energy potential due to glucose utilization, improves regional blood flow in ischemic areas of the brain. Increases of noradrenaline, dopamine and serotonin in the brain, does not affect the levels of GABA, is not associated with either ┬áreceptor has no noticeable effect on the spontaneous bioelectric activity of the brain.

Fenotropil no effect on respiration and the cardiovascular system, displays unspoken diuretic effect , it has anoreksigennoy activity in exchange application.

Phenotropil stimulating effect manifested in its ability to provide a moderately pronounced effect on motor reactions in improving physical performance, expressed antagonism cataleptic effects of neuroleptics and also in reducing the severity of hypnotic action of ethanol and hexenal.

Stimulating effect phenotropil ideatornoy prevails in the area . Moderate inducing effect of the drug is combined with anxiolytic activity, improves mood, has some analgesic effect by raising the pain threshold.

Phenotropil adaptogenic effect is to increase the body’s resistance to stress under conditions of excessive mental and physical stress, with fatigue, hypokinesia and immobilization at low temperatures.

While taking phenotropil marked improvement in vision, which is reflected in an increase in sharpness, brightness and field of view.

Fenotropil improves blood flow equipoise definition to the lower extremities.

Phenotropil stimulate antibody production in response to antigen indicating its immunostimulatory properties, but at the same time it does not promote immediate hypersensitivity and allergic inflammatory changes of the skin reaction induced by the introduction of the foreign protein.

In exchange application phenotropil not develop drug dependence, tolerance and “withdrawal syndrome”.

Action phenotropil seen with a single dose, which is important when using the drug in extreme conditions.

Fenotropil has no teratogenic, mutagenic, carcinogenic and embryotoxic properties. Toxicity – low lethal dose in the acute experiment is 800 mg / kg.


Fenotropil rapidly absorbed, it equipoise definition penetrates into the various organs and tissues, readily passes through the blood-brain barrier. The absolute bioavailability after oral administration is 100%. Maximum concentration in blood reached after 1 hour half-life of 3-5 hours. Fenotropil not metabolized by the body and excreted from the body unchanged. Approximately 40% of the drug is excreted in urine and 60% of the drug is excreted in the bile and sweat.