Paracetamol has analgesic and antipyretic action, due to its influence on the thermoregulatory center in the hypothalamus; eliminates headache and other types of pain, increased temperature reduces. Ascorbic acid  is involved in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, in the corticosteroids synthesis of collagen and procollagen; normalizes capillary permeability. It increases the body’s resistance, which is associated with the stimulation of the immune system.
Pheniramine – blocker of equipoise histamine receptors and reduces rhinorrhea, nasal congestion feeling, sneezing, watery eyes, itching and reddening of the eyes.


Acute respiratory viral infections (symptomatic therapy), nasopharyngitis.



  • Hypersensitivity to paracetamol, ascorbic acid, pheniramine or any other component of the formulation.
  • Erosive and ulcerative lesions of the gastrointestinal tract (exacerbation).
  • Renal insufficiency.
  • Portal hypertension.
  • Alcoholism.
  • Deficiency of glucose-6-phosphate dehydrogenase.
  • Children’s age (15 years).
  • Pregnancy  and lactation.

Be wary – liver failure, angle-closure glaucoma, prostatic hyperplasia, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), viral hepatitis, alcoholic hepatitis, old age.

Dosing and Administration

Inside – 1 sachet 2-3 times per day. The drug equipoise should be completely dissolved in a glass of warm water and the resulting solution immediately drink. It is better to take the drug between meals. The interval between doses of the drug should be at least 4 hours.
In patients with impaired hepatic or renal function and in elderly patients with an interval between doses of the drug should be at least 8 hours.
The duration of intake without consulting your doctor no more than 5 days in the appointment as an analgesic and 3 days as antipyretic.

Side effects

The drug was well tolerated at recommended doses.
Nausea, epigastric pain, allergic reactions (skin rash, pruritus, urticaria, angioedema).
Rare – a violation of hematopoiesis (anemia, thrombocytopenia, methemoglobinemia), dry mouth, paresis of accommodation, urinary retention, drowsiness.
prolonged use at doses considerably higher than recommended, increasing the likelihood of human liver and kidneys, it is necessary to monitor patterns of peripheral blood.
About all the side effects of the drug should be reported to your doctor.

Overdose (due to paracetamol)

Symptoms: pale skin, loss of appetite, nausea, vomiting; gepatonekroz (necrosis due to the severity of intoxication is directly dependent on the degree of overdose). Toxic effects in adults may, after receiving more than 10-15 g of paracetamol: increased activity of “liver” transaminases, increased prothrombin time (after 12-48 hours after admission); detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely liver failure develops lightning speed and can be complicated by renal insufficiency (tubular necrosis).
Treatment: in the first 6 hours after overdose – gastric lavage, introduction of donators of SH-groups and precursors of glutathione synthesis – through methionine 8-9 h after the overdose and N-acetylcysteine through 12 h. The need for additional therapeutic measures (further introduction of methionine in / with the introduction of N-acetylcysteine) is determined by the concentration of paracetamol in the blood, as well as the time elapsed after the reception.

Interaction with other drugs

Ethanol enhances the sedative effect equipoise of antihistamines.
Antidepressants, antiparkinsonian agents, antipsychotic agents (phenothiazines) – increase the risk of side effects (urinary retention, dry mouth, constipation). Corticosteroids – increase the risk of developing glaucoma.
Inductors microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, which makes the possibility of severe intoxication with small overdoses. Ethanol contributes to the development of acute pancreatitis.
Inhibitors of microsomal oxidation (including cimetidine) reduce the risk of hepatotoxicity.
Paracetamol reduces the effectiveness of uricosuric drugs.

special instructions

The product does not contain sugar and can be used in patients with diabetes mellitus.
When receiving metoclopramide, domperidone or cholestyramine also need to consult with your doctor.
It is possible distortions in the laboratory tests for the quantitative determination of the concentration of uric acid and glucose in plasma.
In order to prevent liver toxicity of paracetamol should not be combination with alcohol, and take people prone to chronic alcohol consumption.
The risk of liver damage increases in patients with alcoholic hepatosis.